Recently studies have shown that intravitreal injection of ranibizumab is effective for age related macular degeneration. However there are problems about injection regimen of maintenance phase. We plan to perform new simplified treat and extend regimen using ranibizumab.
The purpose of the present study is to evaluate the simplified treat and extend regimen using ranibizumab in eyes with wet age related macular degeneration about best-corrected visual acuity, central retinal thickness, the disappearance rate of the morphological change and treatment continuous rate.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
50
0.5mg/0.05ml, intravitreal injection, frequency: each 8 or 12 weeks
Mie University Graduate School of Medicine
Tsu, Japan
RECRUITINGA change from baselines best corrected visual acuity at 24 months
Time frame: 24 months
A drop-out rate of the 3 and 12 months
Time frame: 3 and 12 months
A treatment continuance rate until 24 months
Time frame: 24 months
A change of best corrected visual acuity at 12 months
Time frame: 12 months
A change from baselines central retinal thickness measured by spectral domain optical coherence tomography at 12 and 24 months
Time frame: 12 and 24 months
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