Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers

Inclusion Criteria: A subject will be eligible for inclusion in this study only if all of the following criteria apply: 1. Healthy, as determined by a responsible physician, based on a medical evaluation including medical history, physical examination and laboratory tests carried out within 28 days prior to administration of eASCs (if applicable) and LPS. A subject with a clinical abnormality or laboratory parameter outside the reference range may be included only if the investigator judges that the finding is unlikely to introduce additional risk factors and will not interfere with the study procedures 2. Male aged between 18 and 35 years, inclusive at the time of signing the informed consent 3. Male subjects (including those who have had a vasectomy) must agree to use barrier contraception (latex condoms) when engaging in activity in which conception is possible while on study medication and for at least 28 days after taking the last dose of study medication 4. Must understand and voluntarily sign an informed consent form prior to the conduct of any study related assessment/procedures. Capable of giving written informed consent and able to comply with the requirements and restrictions listed in the informed consent form. Exclusion Criteria: Subjects meeting any of the following exclusion criteria are not to be enrolled in the study: 1. Subject has had a major illness in the past 3 months or any significant chronic medical illness that the investigator would deem unfavourable for enrolment, including inflammatory diseases 2. Subjects with a history of malignancy 3. Significant concurrent, uncontrolled medical condition including, but not limited to, renal, hepatic, hematological, gastrointestinal, endocrine, pulmonary, neurological, cerebral psychiatric disease, or evidence of demyelinating disease 4. Subject uses tobacco products 5. Subject has a history, within 3 years, of drug abuse (including benzodiazepines, opioids, amphetamine, cocaine, THC, methamphetamine) 6. History of alcoholism and/or drinking more than 5 units of alcohol per day 7. Any clinically relevant abnormality noted on the 12-lead ECG as judged by the investigator or an average QTc \> 450 msec 8. The subject has received an investigational product within three months prior to day 1 of the current study 9. Use of prescription or non-prescription drugs and herbal and dietary supplements within 6 months unless in the opinion of the investigator the medication will not interfere with the study procedures or compromise subject safety 10. Transfusion of blood or blood products within 6 months prior to the inclusion in the study. 11. Subject has difficultly in donating blood or accessibility of a vein in left or right arm. 12. Subject has donated more than 350 mL of blood in last 3 months 13. Body mass index \>28 kg/m2 14. Presence of a severe bleeding or thrombotic disorder 15. History of known pulmonary embolism or known secondary anti-phospholipid syndrome 16. Subjects known or suspected of not being able to comply with a study protocol (e.g. due to alcoholism, drug dependency or psychological disorder) 17. Known allergies or hypersensitivity to antibiotics, HSA, DMEM, materials of bovine origin, and Ringer's Lactate Solution 18. Any other issue that, in the opinion of the investigator, could be harmful to the subject or compromise interpretation of the data.