The recurrent rate of CBDS in patients with recurrent CBDS is high. It was reported that up to 60% of patients had stone recurrence within two years after stone retrieval by ERCP. Although EPLBD is useful for for extraction of large CBDS with less operation time and mechanical lithotripsy.It is not known whether EPLBD could prevent the recurrence in patients with recurrent CBDS.Although Harada et al found that EPLBD might reduce the short-term recurrence of CBD stones in patients with previous ES. It is a retrospective study with a small sample size (n=94). Here a prospective, randomized controlled study including two tertiary centers was designed. The aim of this study was to investigate whether EPLBD could reduce the recurrence rate in patients with recurrent CBDS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
180
For the patients in EPLBD group, a CRE balloon (diameter 10, 11, 12, 13.5, 15 mm; Boston Scientific) was chosen according to the diameter of bile duct. It was placed across the papilla orifice and then gradually filled with diluted contrast. When the waist disappeared, the balloon was kept inflated for 120s. The stones were then retrieved by a basket or a retrieval balloon.Mechanical lithotripsy was used if necessary
Xijing Hospital of Digestive Diseases
Xi'an, Shaanxi, China
The First Affiliated Hospital Of Xi'an Jiaotong University
Xi'an, Shaanxi, China
Recurrent rate of CBDS within two years after ERCP
Within the two years after ERCP, CBDS was found again by CT, MRCP, ERCP or biliary surgery
Time frame: up to 2 years
recurrent time
Time frame: up to 2 years
success rate of stone extraction
Time frame: up to 2 years
success rate of stone extraction in the initial attempt
Time frame: up to 2 years
performance time of ERCP
Time frame: up to 2 years
rate of mechanical lithotripsy
Time frame: up to 2 years
post-ERCP complication
Time frame: up to 2 years
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