To compart differences on the effect on core temperature between anesthetic induction with intravenous propofol versus inhalation induction with sevoflurane
Hypothermia occurs with anesthetic induction due to redistribution hypothermia. Hypothermia has adverse effects and should be avoided or minimized. Intravenous propofol induction is the most common technique used for anesthetic induction. There is preliminary evidence that there is less redistribution hypothermia when anesthetic induction is achieved by inhalation induction compared to intravenous induction. There is not enough data to compel a change in practice patterns. This study will enroll a larger number of patients in order to provide stronger evidence that there is a significant difference between induction techniques on body temperature. Patients will be randomly assigned to two variation of inhalation induction techniques and two variations of intravenous induction. The effect on temperature between the four groups will be compared. Reducing the degree of hypothermia has the potential to decrease surgical infection rate as well as providing other benefits to patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
331
Standard anesthesia care will be provided after induction based on randomization. Temperatures will be monitored every 15 minutes
Albert EinsteinMedical Center
Philadelphia, Pennsylvania, United States
Measurement of Core Temperature
Core temperature at 15 minute intervals
Time frame: intraoperative
Temperature Below 36.0 Degrees C
Percentage of patients who had at least one temperature below 36.0 degrees C in the first hour of anesthesia
Time frame: Intraoperative
Measurement of Blood Pressure
Blood pressure decrease after intravenous anesthetic induction
Time frame: intraoperative
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