Observational vs. Ablative Treatment for Low-grade Squamous Intraepithelial Lesions.

Saint Thomas Hospital, Panama250 enrolled

Overview

To evaluate the rate of regression and progression of low-grade squamous intraepithelial lesion comparing expectant vs. ablative treatment.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

250

Conditions

LSIL, Low-Grade Squamous Intraepithelial Lesions

Interventions

Ablative treatmentPROCEDURE

Use of an ablative treatment (cryotherapy) for the management of Low-Grade Squamous Intraepithelial Lesions of the cervix.

Expectant managementPROCEDURE

Patients diagnosed with Low-Grade Squamous Intraepithelial Lesions were managed with observation and evaluation at 6 and 12 months after diagnosis.

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of Low-Grade Squamous Intraepithelial Lesion by cervical cytology. * Positive Biopsy for Low-Grade Squamous Intraepithelial Lesion after colposcopy. Exclusion Criteria: * Serological detection of human immunodeficiency virus (HIV).

Locations (1)

Saint Thomas H

Panama City, Provincia de Panamá, Panama

Outcomes

Primary Outcomes

Number of patients diagnosed with Low-Grade Squamous Intraepithelial Lesions that progressed to a higher level lesion (High Grade or cervical cancer) when evaluated at 6 and 12 months after diagnosis.

Time frame: 12 months

Secondary Outcomes

Number of patients diagnosed with Low-Grade Squamous Intraepithelial Lesions that regressed to a higher level lesion (High Grade or cervical cancer) when evaluated at 6 and 12 months after diagnosis.

Time frame: 12 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.