The purpose of this study is to investigate the patient characteristics, selection of treatment, and factors associated with clinical outcomes in Japanese patients with acutely decompensated congestive heart failure.
Congestive heart failure (CHF) has been markedly increasing in Japan due to the rapid aging of the society and the Westernization of lifestyle that facilitates the development of coronary artery disease. The prognosis of patients with CHF still remains poor, despite the recent advances in medical and surgical treatment. Elderly heart failure patients with preserved ejection and multiple comorbidity may account for significant portion among CHF patients in the real world clinical practice, however; most of previous prospective cohort studies excluded these patients. The KCHF registry, an all-comer, prospective, multicenter registry, was designed to investigate all patients who admitted to the hospital due to acutly decompensated CHF. The aim of this study was to clarify the patients characteristics , selection of treatment, and prognosis of patients with acutly decompensated CHF in the real-world clinical practice in Japan.
Study Type
OBSERVATIONAL
Enrollment
4,056
Standard management
Department of Cardiovascular Medicine, Kyoto University Hospital
Kyoto, Japan
hospital mortality
Time frame: 1-year
functional level at discharge measured by NYHA classification
Time frame: 1-year
improvement of dyspnea level at discharge measured by Likert scale
Time frame: 1-year
walking ability at discharge categorized by ambulatory, wheelchair (outdoor only), wheelchair (outdoor and indoor), bedridden
Time frame: 1-year
any severe ventricular arrhythmic event during hospitalization
Time frame: 1-year
onset of atrial fibrillation events during hospitalization
Time frame: 1-year
any bradyarrhythmic event during hospitalization
Time frame: 1-year
any stroke during hospitalization
Time frame: 1-year
any cardiac surgery during hospitalization
Time frame: 1-year
any cateter intervention during hospitalization
Time frame: 1-year
any device implantation during hospitalization
Time frame: 1-year
bleeding events during hospitalization (GUSTO definition; moderate to severe)
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Time frame: 1-year
adverse drug events during hospitalization
Time frame: 1-year
infectious diseases during hospitalization
Time frame: 1-year
change of BNP at discharge (≧30% compared to BNP at admission )
Time frame: 1-year
worsening renal function at discharge (raise of Cr≧0.3mg/dl compared to Cr at admission )
Time frame: 1-year
usage of guideline recommended medicine during hospitalization
Time frame: 1-year
usage of tolvaptan during hospitalization
Time frame: 1-year