Irreversible Electroporation(IRE) For Unresectable Renal Tumors

Inclusion Criteria: * unresectable kidney tumors * patients refused surgical therapy * Karnofsky-index \>70% * Age ≥ 18 and ≤ 80 years * life expectancy ≥ 12 month * compliance of the patient taking part in a study * informed consent Exclusion Criteria: * violation against one or more inclusion criteria * an estimated glomerular filtration rate (eGFR) of \< 30 mL/min/1.73 m2 * QT-interval \>550 ms or cardiac arrhythmias or condition after myocardial infarction, that make an ECG-synchronisation unfeasible * active infection or severe health interference, that make taking part in a study unfeasible * pregnancy, lactation period * general contraindications for anesthesia, endotracheal anesthesia and muscle relaxation * psychiatric disorders that make taking part in a study or giving informed consent unfeasible * haemorrhage, impossible intermission of taking blood thinner, untreatable thrombophilia * thromboplastin time ≤50 %, thrombocytes ≤50 Gpt/L; partial thromboplastin time \>50 * untreated urinary retention * severe hepatic dysfunction * any other clinically important renal, hematological, metabolic, neurological, gastrointestinal, hepatic or pulmonary disorders or dysfunctions preventing study participation (investigator's assessment) * taking part in another clinical study for renal tumor.