Long Protocol and Growth Hormone in Poor Responders

Woman's Health University Hospital, Egypt240 enrolled

Overview

The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the addition of growth hormone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

240

Conditions

Infertility

Interventions

Growth hormoneDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 44 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Poor responder females are those who posses two out of these three criteria: * Female age ≥40 years * Females who have at least one previous cancelled IVF cycle * POR according to AFC ≤ 5 or low AMH value. Exclusion Criteria: * Females over 45 years * Females with FSH more than 20 IU/l * Females with previous ovarian surgery * Females suffering from causes of infertility other than poor ovarian response * Females refusing to be enrolled in the study

Locations (1)

Kasr el aini hospital

Cairo, Egypt

Outcomes

Primary Outcomes

Live birth rate

Fresh, Frozen, Cumulative

Time frame: 12 months

Data from ClinicalTrials.gov

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