Study of Heat and Intravenous Fluids for Exogenous Rewarming

Stanford University8 enrolled

Overview

The purpose of this study is to compare two novel active rewarming techniques in mildly hypothermic people. Volunteers will undergo 3 cooling trials in a circulating bath at 14 degrees celsius and will then be rewarmed with either shivering alone, warmed iv fluids (IVF), or water perfusion pads applied to the hands and feet. The investigators hypothesize that both heated IVF and water perfusion pads to the arteriovenous anastomoses (AVAs) will prove to provide significantly superior rewarming rates than shivering alone.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hypothermia

Interventions

Warmed IV fluidsOTHER

1 Liter of warmed IV fluids at 42 degrees celsius

Warmed perfusion padsOTHER

Neoprene perfusion pads placed on the palms and soles to rewarm through focusing on the arteriovenous anastomoses

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Any healthy male or female over 18 years of age Exclusion Criteria: * No heart/blood pressure/cholesterol medications. * No history of Raynaud's disease or any other condition (including asthma) that could be aggravated by cold-water immersion

Outcomes

Primary Outcomes

Rate of rewarming

Track to rate of rewarming of each arm

Time frame: 60 minutes

Data from ClinicalTrials.gov

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