Randomized trial of supplying a cold vest as compared with controls (no cold vest) on cardiovascular risk factors such as blood lipids, insulin, blood pressure and body weight and also on basal metabolic rate. Recruitment of 100 participants and 70 are randomized to being given a vest which they can use to increase basal metabolic rate during 1-2 hours (as long as the pre-cooled vest stays cool) by activating brown adipose tissue and/or shivering. The remaining 30 subjects will constitute a control group. Lab tests and anthropometrics are checked at baseline, after 2 months and after 1 year.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
50
The lowering of body temperature increases basal metabolic rate
University Hospital of Linkoping
Linköping, Sweden
basal metabolic rate
basal metabolic rate measured in the fasting state by indirect calorimetry
Time frame: up to 1 year
Composite measure of cardiovascular risk factors
Blood lipids, insulin, body weight, blood pressure
Time frame: up to 1 year
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