The purpose of this study is to evaluate the pterygium vascularity and size before and after intralesional ranibizumab injection and to evaluate its recurrence rate following pterygium excision surgery.
The purpose of this study is to: 1. Compare the vascularity of primary pterygium before and 1 week after intralesional ranibizumab (0.3 mg/0.03 mL) injection. 2. Compare the size of primary pterygium before and 1 week after intralesional ranibizumab (0.3 mg/0.03 mL) injection. 3. Compare the recurrence rate at 1 year after pterygium excision surgery between the group with and without intralesional ranibizumab injection.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
36
Intralesional ranibizumab 0.3 mg/0.03mL injected 1 week before pterygium excision surgery.
pterygium recurrence
pterygium recurrence is defined as true recurrence with a fibrovascular tissue invading the cornea (grade 4 lesion)
Time frame: 1 year
pterygium vessel area
Pterygium vesel area is defined as the as the ration of pixels occupied by the vessels within the pterygium area in percentage.
Time frame: 1 week
corneal pterygium area
Corneal pterygium area is defined as the as the ration of pixels occupied by the pterygium within the cornea area in percentage.
Time frame: 1 week
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