Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections?

Neslihan Uztüre75 enrolled

Overview

This study was aimed to investigate the impact of using different epidural volumes. Patients with acute discogenic pain were included in the study.

Objectives: This study was aimed to investigate the impact of using different epidural volumes. Methods: Seventy five patients with acute discogenic pain were included in the study.The patients were randomly assigned to three groups. All patients received a single epidural dose of triamcinolone \[80 mg\] and 12.5 mg bupivacaine combination. The patients in Group 1, Group 2 and Group 3 received a volume of 10 mL, 15 mL, and 20 mL by epidural injections, respectively. The efficacy of treatment was assessed with VAS (visual analog scale) \[O= no pain, 10 = unbearable pain\], SLET(straight leg elevation test) \[0° = worst, 85° = best\], and Oswestry Disability Index; ODI \[0% to 20%:minimal disability , 80% to 100%:bed bound patients\] before and 2 weeks after the EPSI.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Pain

Interventions

TriamcinoloneDRUG

Triamcinolone

Epidural VolumeDRUG

Epidural Volume

BupivacaineDRUG

Bupivacaine

Eligibility

Sex: ALLMin age: 25 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * acute discogenic pain with less than three months duration not responding to other modalities of conservative management \[NSAIDs, physiotherapy, bracing, etc.\], * radiological disc bulging accompanying unilateral root impingement symptoms, * an Oswestry daily activity score more than 20 percent, and * resistance to treatment. Exclusion Criteria: * Patients with bilateral root impingement symptoms, neurological deficits, and/or history of previous lumbar disc surgery, severe cardiac, pulmonary, gastrointestinal, renal diseases, glaucoma, urinary retention, and/or known allergy to the drugs used in the study were excluded from the study.

Outcomes

Primary Outcomes

VAS (visual analog scale) [O= no pain, 10 = unbearable pain]

Time frame: 2 weeks

SLET(straight leg elevation test) [0° = worst, 85° = best]

Time frame: 2 weeks

Oswestry Disability Index; ODI [0% to 20%:minimal disability , 80% to 100%:bed bound patients]

Time frame: 2 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.