CogStim, a Pilot Study : Cognitive Rehabilitation Management of HIV-1 Mild Cognitively Impaired Patients Controlled With Antiretroviral Therapy

Inclusion Criteria: * \- Seropositive for HIV-1 Patient * With a plasma viral load below the limit of detection for minimum 6 months (HIV viral load \<40 copies / ml) * On stable antiretroviral therapy for 12 months, according to the revised optimized subject to the constraints of genotypic resistance and CPE score in the absence of cons-indication to treatment intensive brain penetration (Annex 15) * With cognitive complaint objectified by the cognitive complaint questionnaire (Appendix 9: score 3 or 1 positive response among the items C4, C5, C7, C8) and cognitive impairment found by an alteration of at least two cognitive fields assessed by psychometric tests for at least 6 months * 18 \<age \<55 years * No defined by a marked depression scale score of Beck \<16 (Appendix 13) * No marked anxiety defined by a T score\> 55 on the scale of Spielberger STAI-Y (Annex 14) * Insured under the social security * Who signed the consent form. * Recent brain imaging excluding other causes of cognitive impairment (MRI or CT brain injected injected so-indication against MRI) Exclusion Criteria: * A patient diagnosed and followed for more than six months psychiatric disorder that could interfere with psychometric assessment * Patients with a poor understanding of French, * Patients with active opportunistic infection of the CNS or with neurological sequelae. * History of head trauma * Active Substance excluding cannabis * Patient for which a change of antiretroviral therapy is provided within 12 months * Patient for which interferon treatment is provided within 12 months * Patient placed under guardianship, * Patient with HIV-related dementia * Liver cirrhosis Child B or C (Annex 16) * Severe renal impairment (creatinine clearance by Cockcroft \<30 ml / min)