Safety of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Erectile Dysfunction

Inclusion Criteria: Postprostatectomy Erectile Dysfunction * A man aged 20 or older * Who is willing to consent to participate in the study concerned with improving sexual activity after prostatectomy, the man has maintained normal sexual activity prior to prostatectomy * Prior to prostatectomy PSA (prostate specific antigen) level\<10 ng/mL * At the time of Prostatectomy, Pathological Gleason sum ≤7 * At the time of Prostatectomy, Pathological stage ≤ T2c * 2 years or more postprostatectomy patients with PSA level ≤ 0.04 ng/mL without additional therapy after prostatectomy * Who cannot satisfy sexual activity(more than 4 times) with proper sexual stimulation in spite of taking maximum dose of oral PDE5I(phos-phodiesterasetype-5 inhibitors) within last 8weeks. * IIEF, EF(erectile function) domain score is under 17 * Have a consistent partner who is willing to engage in sexual activity more than twice per month during the study. Diabetes-associated Erectile Dysfunction * HbA1c is between 6.5% and 10% of man over 20 years of age with diabetes * Who cannot satisfy sexual activity(more than 4 times) with proper sexual stimulation in spite of taking maximum dose of oral PDE5I within last 8weeks. * IIEF, EF domain score is under 17 * Who is willing to consent to participate in the study concerned with improving sexual activity * Have a consistent partner who is willing to engage in sexual activity more than twice per month during the study. Exclusion Criteria: * History of bone marrow disorders * Serum AST/ALT \> 3 X upper limit of normal or Creatinine \> 1.5 X upper limit of normal * History of hypersensitivity against a gentamycin * Severe cardiovascular disease(angina, arrhythmia, cardiac failure, stroke), kidney failure, respiratory failure * Positive for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis test * Positive for PSA or CEA or AFP (Carcinoembryonic antigen), history of cancer in the last five years (except Prostatic cancer) Uncontrolled hypertension or hypotension (systolic blood pressure \> 170 or \< 90 mm Hg, diastolic pressure \> 100 or \< 50 mm Hg) * HbA1c exhibit greater than 10% * Men on anticoagulant treatment * Have a severe infectious disease * Testosterone level is less than 200ng/dl * Have a penile implant or willing to it * Patients with morphological changes of the penis * Patient's partner is trying to conceive during the trial period * Unwilling to participate in the study * Participating in other clinical trials in the past 30 days * Unable to compliance with protocol * Inappropriate patients to participate in the study according to the investigator