Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss

* Be between ages 50-89 years old * American-English speaking * Have difficulty hearing speech in a noisy environment * No recent history of middle ear disease * No severe insomnia, major depressive disorders, severe anxiety or post-traumatic stress disorder * Not a current or previous user of hearing aids. You are eligible if you were noncompliant and stopped wearing a hearing aid device \>6 months earlier for intermittent use or \>3 years if you were a full-time consistent user of hearing aid devices * Not be dependent on alcohol or drugs * Have not participated in another research study within 30-days * If female, you must confirm to be non child bearing (post-menopausal for at least 12-months or surgically sterile) * If male, you must confirm to use a barrier method (condom) * Not be a professional musician * No history of important cardiac, endocrine, pulmonary, neurologic, psychiatric, hepatic, renal, hematologic, immunologic, or other major disease deemed clinically significant by the study doctor While you are in the study, you must: * Follow the instructions you are given * Come to the study centre for all visits with the study doctor or study staff * Answer the telephone at the scheduled date and time for the 2 telephone calls * Tell the study doctor or study staff about any changes in your health or the way you feel * Tell the study doctor or study staff if you want to stop being in the study at any time * Bring your Diary to each visit * Not eat or drink anything containing Grapefruit beginning 7-days before Baseline visit (Visit 3, Day 1) until the end of the study * Use sun screen if you plan to sunbathe * Not use headphones or headsets at high volume * Not use hearing aids or devices at any time during the study