Does Benign Prostatic Obstruction Cause Hypertension?

St. Olavs Hospital20 enrolled

Overview

The known correlation between benign prostatic hypertrophy (BPH) and hypertension could be explained by 3 theoretical pathway models. Whether hypertension causes BPH, BPH causes hypertension or the two are caused by a common factor is currently unknown. In this study it will be investigated whether hypertension is due to the direct effects of infravesical obstruction to urinary outflow in patients with benign prostatic hyperplasia. The approach will be blood pressure measurement in patients who will have a resection of the prostate.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Prostatic Hyperplasia Hypertension

Interventions

24-hr ambulatory blood pressure measurementPROCEDURE

Eligibility

Sex: MALEMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Listed for inguinal hernia repair or hydrocele repair or transurethral resection of the prostate * signed informed consent Exclusion Criteria: * Treatment with antihypertensive medication that has been started within 3 months of inclusion. * Treatment with antihypertensive medication that has been started after inclusion and before final blood pressure measurements have been obtained 6 months after operation. * Any reason that the investigator deems that the participant will not comply with follow-up.

Locations (1)

St Olavs Hospital, Department of Urology

Trondheim, Norway

Outcomes

Primary Outcomes

change in blood pressure

one measurement 6 weeks pre-surgery, and ambulatory measurement during 6 months post-surgery

Time frame: 7,5 months

Secondary Outcomes

prostate symptom severity assessed by 'International prostate severity score' (questionnaire)

assessed by 'International prostate severity score' (questionnaire)

Time frame: 7,5 months

Data from ClinicalTrials.gov

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