Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm, Multicenter Study

Inclusion Criteria: * Adults (≥ 22 years) * Self-report of daytime somnolence * Body mass index (BMI) ≤ 32 * Mild to moderate obstructive sleep apnea (AHI 10 - 30; lowest O2 sat ≥ 80%) * Evidence of palate and tongue base collapse on supine fiberoptic examination * Non-compliant with or refusal of continuous positive airway pressure therapy (CPAP) (\< 4 hours per night by patient report) * No prior surgical treatment for OSAS other than nasal surgery * Willing and capable of providing informed consent Exclusion Criteria: * Another significant sleep disorder (e.g., insomnia, periodic limb movement) * Tonsillar hypertrophy * Chronic Obstructive Pulmonary Disease (COPD) * Interstitial Lung Disease (ILD) * Cystic Fibrosis * Acute Repiratory Distress Syndrome (ARDS) * Nasal or supraglottic obstruction on fiberoptic examination * American Society of Anesthesiologists (ASA) class III ,IV, V * Latex allergy * Lidocaine allergy * Pregnancy or plans to become pregnant Note: women of childbearing potential must demonstrate a negative pregnancy test upon enrollment; those patients qualified to progress to RFA must also demonstrate a negative pregnancy test within 7 days prior to the date of RFA procedure. * Major depression or non-stabilized psychiatric disorder * Drug or alcohol abuse * Previous palatal or tongue surgery * Stable or unstable angina * congestive heart failure (CHF) * moderate or severe valvular disease * transient ischemic attack (TIA)/cardiovascular accident (CVA) * Carotid stenosis or endarterectomy * Anemia * Room air oxygen saturation (SpO2) \< 95% * Pulmonary hypertension * Dialysis * Central or mixed apnea ≥ 10% of respiratory events * Participation in another clinical study (enrolled in any concurrent study) whose investigational plan is judged to interfere or affect any of the measures of this study