Placental Protein 13 Serum Endoglin and Uterine Doppler Indeces as Predictors of Pre-eclampsia

Cairo University50 enrolled

Overview

50 pregnant females were divided in two groups, twenty five as a control group and twenty five as high risk group; they were subjected to uterine artery Doppler, measurement of maternal serum and detection of (MTHFR) gene polymorphisms in first trimester at 11 to 14 weeks of gestation, all pregnancies were followed until 40 weeks for development of pre-eclampsia

50 pregnant females were divided in two groups, twenty five as a control group and twenty five as high risk group; they were subjected to uterine artery Doppler, measurement of maternal serum (pp-13) and detection of (MTHFR) gene polymorphisms in first trimester at 11 to 14 weeks of gestation, all pregnancies were followed until 40 weeks for development of pre-eclampsia

Study Type

OBSERVATIONAL

Enrollment

Conditions

Preeclampsia

Interventions

ultrasound monitoringOTHER

Uterine artery Doppler assessment

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * pregnant women at 11 to 14 weeks of gestation Exclusion Criteria: * fetal anomalies other medical diseases as diabetes mellitus, renal or liver diseases

Locations (1)

Kasr Alainy medical school

Cairo, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

development of preeclampsia

Time frame: 40 weeks pregnancy

Data from ClinicalTrials.gov

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