Package of Interventions After Recovering From Moderate Acute Malnutrition

Washington University School of Medicine1,499 enrolled

Overview

Children who recover from moderate acute malnutrition in Malawi remain at high risk for relapse or death in the year following recovery. This cluster-randomized trial will evaluate a package of affordable, safe, proven interventions specifically targeted to this population of children in an attempt to decrease their risk of relapse or death following recovery from moderate acute malnutrition. These children will be followed for a year following recovery to assess rates of relapse and mortality.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

1,499

Conditions

Malnutrition

Interventions

Lipid Nutrient SupplementDIETARY_SUPPLEMENT

Sulfadoxine-pyrimethamineDRUG

AlbendazoleDRUG

ZincDRUG

Eligibility

Sex: ALLMin age: 6 MonthsMax age: 59 Months

Medical Language ↔ Plain English

Inclusion Criteria: * recovered from moderate acute malnutrition, as defined by mid-upper arm circumference (MUAC) of 11.5-12.4 cm Exclusion Criteria: * not permanent resident in vicinity of site * severe chronic illness * receiving other supplementary food or participating in other research

Locations (1)

St. Louis Nutrition Project

Blantyre, Malawi

Outcomes

Primary Outcomes

Number of children who remain well-nourished (Defined as mid-upper arm circumference (MUAC) > 12.5 cm and without edema)

Defined as mid-upper arm circumference (MUAC) \> 12.5 cm and without edema

Time frame: 12 months

Data from ClinicalTrials.gov

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