The purpose of this study is to find out if giving a medicine called furosemide, which is a diuretic or water pill, after colon surgery will safely shorten the patient's length of hospital stay.
This study will assess if administration of a loop diuretic, specifically furosemide, to achieve euvolemia can safely reduce length of stay following colorectal surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
123
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation.
Gabapentin is a oral drug used to treat seizures, postherpetic neuralgia, and restless legs syndrome.
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Length of Hospital Stay
Participants will be followed for the duration of hospital stay, an expected average of 2-7 days.
Time frame: Up to 7 days
Number of Participants Readmitted to Mayo Clinic Within 30-days
Time frame: Within 30 days of release from hospital
Number of Participants Requiring Nasogastric Tube Placement
Time frame: Up to 7 days
Time to Stool Output
Time frame: Up to 4 days
Number of Participants With Acute Kidney Injury
Acute kidney injury (AKI) refers to an abrupt decrease in kidney function, resulting in the retention of urea and other nitrogenous waste products and in the dysregulation of extracellular volume and electrolytes. The term AKI has largely replaced acute renal failure (ARF), reflecting the recognition that smaller decrements in kidney function that do not result in overt organ failure are of substantial clinical relevance and are associated with increased morbidity and mortality. The AKI experienced by these patients was not considered an adverse event.
Time frame: Up to 7 days
Number of Participants With Hypokalemia
Hypokalemia is generally defined as a serum potassium level of less than 3.5 mmol/L.
Time frame: Up to 7 days
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