The purpose of this study is to evaluate the effect on distance covered in a 6 minute walking test of Rate Responsive pacing in patients with permanent atrial fibrillation and reduced left ventricular ejection fraction treated with atrioventricular junction ablation and biventricular pacing.
Patients with permanent atrial fibrillation and reduced left ventricular ejection fraction treated with atrioventricular junction ablation and biventricular pacing will be enrolled. Two 6' walking test (6WT), one during VVI 70/min biventricular pacing (RR off) and the other during VVIR 70-120/min biventricular pacing (RR on), will be performed one week apart; patients will be randomly and blindly assigned with a 1:1 ratio to group A (first 6WT RR off) or B (first 6WT RR on). The difference between the two tests will be recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
Rate Response function is turned on in the device. The patients performs a 6 minute walking test. After a week Rate Response function is turned off and the patient performs a second 6 minute walking test.
Rate Response function is turned off in the device. The patients performs a 6 minute walking test. After a week Rate Response function is turned on and the patient performs a second 6 minute walking test.
Università Politecnica delle Marche
Ancona, Ancona, Italy
Policlinico S.Orsola-Malpighi
Bologna, Bologna, Italy
AO Pugliese-Ciaccio
Catanzaro, Catanzaro, Italy
Azienda Ospedaliera "Card. G. Panico"
Tricase, Lecce, Italy
The distance covered during the 6-minute walking test
Time frame: 6 minutes
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Seconda Università Napoli - A.O. Monaldi
Naples, Naples, Italy
AOU "Maggiore della Carità"
Novara, Novara, Italy
Ospedale San Filippo Neri
Roma, Roma, Italy