Bone Mineral Density Status in Pediatric and Adolescent Survivors of Childhood Cancer With History of Bone Fracture

Inclusion Criteria: * History of childhood cancer * Age ≥ 8 years and \< 20 years at time of enrollment * ≥ 2 years since completion of cancer-directed therapy for first cancer * Received chemotherapy for treatment of childhood cancer * History of bone fracture after the conclusion of chemotherapy\* * Not currently receiving cancer-directed therapy * Signed written informed consent (by parent if patient is \< 18 years of age, or by patient, if he or she is ≥18 years of age) * Patient assent for those ≥10 years of age and \< 18 years of age for whom a parent provides informed consent (\*History of bone fracture will be based on patient/parent report of fracture occurrence and will be confirmed in review of the medical record whenever feasible.) Exclusion Criteria: * Current treatment with bisphosphonates (as of time of enrollment) * Current treatment with the anticonvulsant depakote (at time of enrollment) * Currently pregnant