The PK/PD Study of Single Dose of SHR3824 in Healthy Volunteers

Inclusion criteria: * Chinese male and female subjects aged 18 to 45 years. * BMI:18 -25 kg/m2 . * Healthy according to medical history, physical examination findings, 12-lead ECG findings, and clinical laboratory evaluations. Exclusion criteria: * History of or current clinically significant medical illness as determined by the Investigator. * History of clinically significant allergies, especially known hypersensitivity or intolerance to lactose. * Pregnancy or breastfeeding . * Significant acute or chronic medical illness, including renal impairment, or recent surgery. * Donation of blood or plasma within the 4 weeks prior to the start of the study or acception of blood transfusion within 8 weeks.