Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment

N/ACompletedNCT02358772

Charite University, Berlin, Germany658 enrolled

Overview

This is a comparison of clinical outcomes between a pre-hospital and an in-hospital thrombolysis patient registry.

Study Type

OBSERVATIONAL

Enrollment

658

Conditions

Ischemic Stroke

Interventions

thrombolysis in a pre-hospital setting (STEMO concept)OTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Acute ischemic stroke diagnosis with thrombolytic treatment * Admission via EMS * Known premorbid status of need of assistance * NIHSS before treatment available * Time of onset (or last well seen) between 4:00am and 10:30pm Exclusion Criteria: * Unknown time of onset * In-hospital thrombolysis despite decision against treatment because of contraindications in STEMO

Locations (1)

Charité

Berlin, State of Berlin, Germany

Outcomes

Primary Outcomes

modified Rankin Scale (mRS) score

dichotomized mRS 0-1 and 2-6 in patients who lived at home without assistance prior to the index stroke.

Time frame: three months after event

Secondary Outcomes

modified Rankin Scale (mRS) score

dichotomized mRS 1-3 and 4-6

Time frame: three months after event

modified Rankin Scale (mRS) score

mortality (mRS=6)

Time frame: three months after event

modified Rankin Scale (mRS) score

ordinal analysis across whole mRS range

Time frame: three months after event

Data from ClinicalTrials.gov

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