Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage

N/ACompletedNCT02361918

Istanbul University50 enrolled

Overview

Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.

To search for a biomarker, which might be able to predict rectal anastomotic leakage before its clinical presentation. Serum procalcitonin, C-reactive protein, and drain fluid culture, IL-6 and TNF-α levels were evaluated in 50 consecutive patients with rectal cancer who underwent low anterior resection with colorectal anastomosis.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Anastomotic Leakage in Colon Surgery

Interventions

Colon surgeryPROCEDURE

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patient underwent to colonic resection and had drain Exclusion Criteria: * other patients

Outcomes

Primary Outcomes

Predictive values of serum CRP, procalcitonin, drain fluid IL-6 and TNF-alpha levels in anastomotic leakage.

Time frame: 5 day

Data from ClinicalTrials.gov

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