Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Chulalongkorn University15 enrolled

Overview

Comparison of prophylaxis and on-demand treatment in children with moderate to severe hemophilia A. This study determines to compare the efficacy of prophylaxis and on-demand treatment in moderate to severe hemophilia A children in King Chulalongkorn Memorial Hospital, Bangkok, Thailand

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Prophylaxis Hemophilia A

Interventions

prophylaxis treatment, on demand treatmentOTHER

Eligibility

Sex: ALLMin age: 6 MonthsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 6 months to 18 years * Diagnosis severe and moderate hemophilia A Exclusion Criteria: * platelet \< 100,000/mm3 * No factor VIII inhibitor

Locations (1)

pediatric Hemato-oncology department, King Chulalongkorn Memorial Hospital

Pratumwan, Bangkok, Thailand

Outcomes

Primary Outcomes

Number of bleeding episodes require treatment

Time frame: one year

number of school days lost

Time frame: one year

Number of admission days

Time frame: one year

Secondary Outcomes

Joint scores

Time frame: one year

Quality of life score

Time frame: one year

Amount of Facter VIII concentration used

Time frame: one year

Data from ClinicalTrials.gov

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