To optimize a medical device for intradermal injection, knowledge concerning the thickness of epidermis and dermis at the proximal forearm is required. Since scientific knowledge is lacking, the investigators will examine the skin thickness (epidermis and dermis) of adults using imaging technology (High Frequency Ultrasound). The investigators hypothesize that they are able to correlate the thickness of the (epi)dermis to a specific combination of parameters age, gender, and BMI. Based on these results, the investigators can define which needle type and length is needed to correctly perform injections into the dermal layer.
Study Type
OBSERVATIONAL
Enrollment
100
(Epi)Dermal thickness at the proximal forearm and the deltoid region will be measured using imaging technology, more specifically high-frequency ultrasound (20-40 MHz) in B-mode (VEVO 2100®, Visual Sonics). This non-invasive measuring technique has already been proven to be accurate. The echographic measurement will be performed on the left and right deltoid region and on two sides of the proximal forearm. Both the dorsal part and the volar/palmar part of the proximal forearm will be investigated. Ultrasound will be executed using gel (Aquasonic®) to optimize imaging.
Department of Pharmaceutical Sciences; Laboratory of Physiopharmacology; University of Antwerp; Campus Drie Eiken
Wilrijk, Antwerp, Belgium
skin thickness (in milimeters) of the proximal forearm dorsal (both left and right)
Time frame: 10 minutes
skin thickness (in milimeters) of the proximal forearm ventral (both left and right)
Time frame: 10 minutes
skin thickness (in milimeters) of the deltoid region (both left and right)
Time frame: 10 minutes
Body Mass Index
Time frame: at the moment of entering the study
Age
Time frame: at the moment of entering the study
sex
Time frame: at the moment of entering the study
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