Human milk (HM) is considered the gold standard nutrient for infants, which contains a lot of beneficial nutrients such as prebiotics and lactoferrin. Previous studies have shown that both prebiotics and lactoferrin play important roles in generating a bifidobacteria-dominated colonic microflora.The purpose of this study is to investigate the stool characteristics,acceptability, and gastrointestinal tolerance in term infants fed a starting infant formula supplemented with prebiotics and lactoferrin.
Human milk (HM) is considered the gold standard nutrient for infants, which contains a lot of beneficial nutrients such as prebiotics and lactoferrin. Previous studies have shown that both prebiotics and lactoferrin play important roles in generating a bifidobacteria-dominated colonic microflora as well as the intestinal immune systems. The purpose of this study is to investigate the stool characteristics(including intestinal microbiota) acceptability, and gastrointestinal tolerance in infants fed a starting infant formula supplemented with prebiotics and lactoferrin, and compared these data with infants on exclusively breast feeding.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Masking
NONE
Enrollment
65
An infant formula contains prebiotics and lactoferrin
Xin Hua Hospital
Shanghai, Shanghai Municipality, China
growth
Head circumferences and weight gain
Time frame: 6 weeks
Gastrointestinal tolerance and safety
daily records of vomiting and stool characteristics; records of infection episodes and other adverse effects
Time frame: 6 weeks
intestinal microbiota
test the bacteria composition in baby stools by DNA sequencing technology
Time frame: 6 weeks
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