Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G).
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G) to be defined in 3 categories: * elderly FIT (ADL 6; IADL 8; 0 score= 3-4, \< 5 score=2) * elderly UNIFIT (ADL 5; IADL 6-7; 0 score= 3-4, 5-8 score=2; ≥ 80 fit) * elderly FRAIL (ADL ≤ 4; IADL ≤ 5; 1 score= 3-4, \> 8 score=2; ≥ 80 unfit)
Study Type
OBSERVATIONAL
Enrollment
1,300
OS
Overall survival
Time frame: 5 years
PFS
Progression free survival
Time frame: 5 years
FFS
Failure Free Survival
Time frame: 5 years
Response to initial therapy
Time frame: 5 years
Early mortality rate
Time frame: 5 years
% of patients who performed pre-phase therapy
Come to the prefect Therapy is a steroid-based therapy (administered at dosage of at least 25 mg / day) and / or vincristine, which precedes the beginning of the program of chemoimmunotherapy.
Time frame: 5 years
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