Icosabutate - A Phase I, Single Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects

Inclusion Criteria: * males of females * any ethnic origin * Age 18-55 years * BMI 18.0 - 33.0 kg/m2 * generally in good health * signed informed consent Exclusion Criteria: * males or females not willing to use appropriate contraception * recent blood donation * recent blood received * high consumption of alcohol * high consumption of tobacco * subjects who have engaged in heavy exercise last two weeks * prescribed systemic or topical medication taken recently, or supplements/remedies interfering with study procedures or safety * other medication know to alter drug absorption or elimination * abnormal heart rate or blood pressure or 12-lead ECG * significant history of drug allergy, or hypersensitivity to treatment ingredients * ocular disorder requiring topical ocular therapy, or recent allergic eye disease * other significant medical history or physical findings