Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.

Moscow Regional Research and Clinical Institute (MONIKI)

Overview

Assessment of sedative effects of dexmedetomidine and propofol on the clinical course of delirium and neuroinflammation in patients with SIRS using CAM-ICU scale and protein S100b in serum.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Conditions

Delirium

Interventions

DexmedetomidineDRUG

Treatment of delirium by dexmedetomidine i.v. infusion

PropofolDRUG

Treatment of delirium by Propofol i.v. infusion

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * presence of delirium Exclusion Criteria: * presence of Alzheimer's disease * any mental disorder * presence of cancer

Outcomes

Primary Outcomes

CAM-ICU scale

Time frame: up to 5 days

Data from ClinicalTrials.gov

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