PERFECT Project - Part 1 - Study 2

University of Manitoba26 enrolled

Overview

The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse products. We hypothesize that cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake responses compared to non-pulse cereals.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Diabetes Prevention Obesity Prevention

Interventions

ControlOTHER

Non pulse extruded cereal

Pea proteinOTHER

Pulse extruded cereal

Pea starchOTHER

Pulse extruded cereal

Pea fibre + pea starch

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * BMI of 18.5-29.9 kg/m2 Exclusion Criteria: * Restrained eaters * Regularly skip breakfast * Smokers * Competitive sports or athletic training at a high intensity * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year. * Those unable to walk for an hour continuously

Outcomes

Primary Outcomes

Plasma Glucose and Insulin Concentrations

Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits

Time frame: 0 - 200 min

Food Intake

Measured by VAS questionnaire

Time frame: at 120 min

Subjective Appetite

Motivation-to-eat VAS questionnaire

Time frame: 0-200 min

Secondary Outcomes

Palatability of treaments and meal

Measured by VAS questionnaire

Time frame: 5 and 140 minutes

Physical comfort

Measured by VAS questionnaire

Time frame: 0 - 200 min

Energy/fatigue

Measured by VAS questionnaire

Time frame: 0-200 min

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.