Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control

Baskent University60 enrolled

Overview

The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of morfin-related side effects in patients undergoing cesarean section.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Cesarean Section; Dehiscence

Interventions

paracetamolDRUG

Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group P (n = 30) received 1 g iv paracetamol, patients in group S (n = 30) received 100 ml iv %0.9 NaCl

PlaceboDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients between the ages of 20-40 years, * ASA physical status 1-2 who underwent elective cesarean surgery during general anesthesia were included in the study Exclusion Criteria: * A history of allergy to any of the study medications (opiod, general anesthetic agents or paracetamol), * history of opioid or paracetamol use, * hepatic or renal failure, * any psychological disorders, * complications during cesarean section and unable to use PCIA device were excluded from the study.

Outcomes

Primary Outcomes

Postoperative pain scores measured by visual analog scale (VAS)

Time frame: Postoperative 24 hours

Data from ClinicalTrials.gov

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