Background: The cardiac resynchronization therapy (CRT) has been shown to improve symptoms and outcome of patients with congestive heart failure (HF), and depressed left ventricular ejection fraction (LVEF \< 35 %). The rate of non-responders to CRT is estimated at 30 %. Yet, the impact of frailty on the response to CRT has not been studied, until now. Purpose : To assess the impact of frailty in the elderly, on the response to CRT.
Methods : Frailty is evaluated before implant ,and defined as \<14/17 points using the ONCODAGE score, in 150 patients of \> 70 years age, selected for CRT according to the ESC 2013 guidelines. The response to CRT, estimated at 9 months, is defined as an improvement of at least 5 % of the LVEF and the absence of HF hospitalization or cardiovascular death.
Study Type
OBSERVATIONAL
Enrollment
150
CRT device is implanted in all patients selected for the study. Frailty is evaluated before implant and defined as \<14/17 points using the ONCODAGE score
CHU; Service de Cardiologie, Rythmologie et Stimulation cardiaque
Amiens, France
non response on CRT
Time frame: 9 months
seric albumin
To assess the impact of seric albumin on the response to CRT
Time frame: 9 months
seric gammaglutamyltranferase
To assess the impact of seric gammaglutamyltranferase on the response to CRT
Time frame: 9 months
mortality
Time frame: 9 months
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