Test Albuvirtide in Experienced Patients

Inclusion Criteria: 1. 16-60 years old, male or female. 2. Those who meet the Diagnostic Criteria of AIDS and HIV Infection, the Health Industry Standard of the People's Republic of China (WS 293-2008). 3. Those who have been undergoing antiretroviral treatment with nucleosides and non-nucleoside reverse transcriptase inhibitors (NRTIs+NNRTIs) for at least 6 months. 4. HIV-RNA ≥ 1000 copies/mL. 5. Those who have no serious hepatic or renal functional impairment and other parameters are generally in the normal ranges according to the comprehensive physical examinations (including general physical examination, routine blood and urine tests, blood chemistry tests, ECG, etc.). 6. The subjects should have a full understanding of the objective, nature, methods of the trial and the possible reactions. He/She should participate in the trial voluntarily and should sign the informed consent form. Exclusion Criteria: 1. Those who are in an acute stage of infection, or have suffered from AIDS-related diseases (e.g. opportunistic infections or malignant tumors, etc.) at enrollment; or have suffered from opportunistic infections within 3 months prior to enrollment and the conditions have not reached a stable state within 2 weeks prior to enrollment. 2. Those who have used protease inhibitors or HIV fusion inhibitors for antiretroviral treatment, and who have participated in HIV vaccine clinical trials or have participated in other drug trials within recent 3 months. 3. Those who have been co-administered antiviral treatment for hepatitis. 4. Those whose screening test results meet one of the following: hemoglobin \< 9 g/dL, WBC count \<2×109/L, neutrophil count \< 1×109/L, PLT count \< 75×109/L, transaminase \> 3×ULN, total bilirubin \> 2×ULN, creatinine \> 1×ULN, serum creatine phosphokinase \> 2×ULN. 5. Those with allergic constitution or known allergic to ingredients of the investigational drug or ART drugs prescribed in the protocol. 6. Currently suffering from serious chronic diseases, metabolic diseases (such as diabetes mellitus), neurological and psychiatric disorders. 7. Patients with hemophilia A or B. 8. Those with suspected or confirmed history of alcohol or drug abuse. 9. Pregnant or lactating women; or women of childbearing age who refuse to take contraceptive measures during the trial. 10. Those for whom the possibility of being enrolled is low according to the judgment of the investigator (e.g. weak physical condition, poor compliance, etc.).