This study will evaluate the effects of Chen-style Tai Chi compared to conventional exercise in pulmonary rehabilitation for COPD patients. Half of participants will receive the Chen-style Tai Chi intervention, while the other half will receive the conventional exercise intervention. Both groups will receive the same eduction and support during pulmonary rehabilitation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
44
Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Canada
Change from baseline dyspnea at 12 weeks
Dyspnea will be assessed using the chronic respiratory questionnaire (CRQ)
Time frame: Baseline, 12 weeks
Change from baseline lung function at week 12 (Spirometry and whole-body plethysmography)
Spirometry and whole-body plethysmography will be used for baseline and post-training (12 weeks) lung function testing.
Time frame: Baseline, 12 weeks
Change from baseline walking distance at 12 weeks (distance walked during the six-minute walk test)
The distance walked during the six-minute walk test will be used to evaluate the functional exercise capacity of all participants at baseline and post-rehabilitation.
Time frame: Baseline, 12 weeks
Change from baseline exercise capacity at 12 weeks(Endurance time during a constant work rate bicycle ergometry exercise test)
Endurance time during a constant work rate bicycle ergometry exercise test will be used to evaluate the exercise capacity of all participants at baseline and post-rehabilitation.
Time frame: Baseline, 12 weeks
Change from baseline isokinetic quadriceps muscle function at 12 weeks
Voluntary isokinetic quadriceps muscle function will be determined by quantification of force, endurance, and fatigability of the dominant quadriceps during a series of 30 repetitions at an angular velocity of 90°/s of a knee extension test.
Time frame: Baseline, 12 weeks
Change from baseline isometric quadriceps muscle strength at 12 weeks (force of the dominant quadriceps will be measured during a single magnetic stimulation of the femoral nerve)
The force of the dominant quadriceps will be measured during a single magnetic stimulation of the femoral nerve (Twitch force of the quadriceps \[Twq\]) and during a maximum voluntary contraction (MVC).
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Baseline, 12 weeks
Change from baseline physical activity at 12 weeks (participants will be equipped with a physical activity monitor)
To monitor physical activity, participants will be equipped with a physical activity monitor. The device will monitor the daily energy expenditure, the duration of physical activities above the pre-determined intensity level (Metabolic Equivalent of Task (MET) \>3), and also the total daily number of steps.
Time frame: Baseline, 12 weeks
Change from baseline quality of life (QoL) at 12 weeks
In addition to dyspnea (primary outcome), the CRQ will be used also to measure other physical-functional limitations due to COPD with questions related to fatigue and energy levels.
Time frame: Baseline, 12 weeks
Change from baseline health status at 12 weeks (determined with the COPD Assessment test (CAT).
Impact of COPD on a person's life will be determined with the COPD Assessment test (CAT).
Time frame: Baseline, 12 weeks
Change from baseline balance (Berg Balance Test (BBT) at 12 weeks
The Berg Balance Test (BBT) will be used to evaluate the effect of the interventions on patient's balance.
Time frame: Baseline, 12 weeks
Change from baseline of composite serum and plasma biomarkers at 12 weeks
During the baseline assessment and after the rehabilitation program, blood samples from patients will be taken in order to investigate the effect of the interventions on different biomarkers related to systemic inflammation.
Time frame: Baseline, 12 weeks