I125 Brachytherapy After TURP

Inclusion Criteria: * WHO performance status 0-1 * No contra-indication for anaesthesia * No history of irradiation of the pelvis * No other oncologic malignancy except adequately treated basal cell carcinoma of the skin or other malignancy from which the patient is disease free for at least 5 years. * Absence of any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; Prostate (cancer) related: * Histologically proven prostate cancer (adenocarcinoma) of low or intermediate risk following the D'Amico classification. * Prostate volume \< 50 cc as measured on transrectal ultrasound * Neo-adjuvant antiandrogen hormonal treatment is permitted to downsize the prostate volume or to cover waiting time till brachytherapy procedure. No adjuvant hormonal treatment is permitted. * History of TransUrethral Resection of the prostate (TURp), performed at least 3 months before the brachytherapy procedure. * Rim of prostate tissue of at least 1 cm around the post-TURp urethral defect at thepostero-lateral sides of the prostate * Absence of significant TURp-induced urinary incontinence * IPSS \<15 Exclusion Criteria: * Locally advanced (stage T3 or T4 , or metastatic (stage N+ or M+) prostate cancer High grade tumours defined by Gleason score 8 or above Co-morbidity which would exclude the patient from a transperineal implant procedure. Unable to give informed consent.