This is a randomized, single-center, open-label, 2-sequence, 2-period, single-dose, crossover study to assess the bioequivalence and the total 24-hour urinary glucose excretion (UGE) of 400 mg LX4211 administered as a single 400-mg tablet compared to 2 × 200-mg tablets in healthy subjects under fasted conditions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Lexicon Investigational Site
Dallas, Texas, United States
AUC
Time frame: Days 1 to 5, Days 9 to 13
Urinary Glucose Excretion (UGE)
Time frame: Day 1, Day 9
# of Adverse Events
Time frame: Day 1-Day 14
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