Exparel as a Nerve Block for Severe Hand Pain

Phase 3TerminatedNCT02374320

Jose Soberon, MD13 enrolled

Overview

The purpose of this study is to investigate whether the use of the study drug (Exparel) is safe and effective for treating circulation problems and pain in the hand or fingers.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

CREST Syndrome Peripheral Vascular Disease Raynaud Disease Scleroderma, Diffuse

Interventions

liposomal bupivacaineDRUG

injected as an axillary block

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * American Society of Anesthesiologists (ASA) status I-IV Exclusion Criteria: * True Allergy, not sensitivity to: local anesthetics, midazolam, fentanyl, propofol, ketamine * Previous surgery or significant trauma involving the radial or ulnar arteries (previous history of angiography and intravascular catheter placement are permitted) * Pregnancy * Severe hepatic impairment * Evidence of infection at or near the proposed needle insertion site * Any sensorimotor deficit of the ipsilateral upper extremity, whether acute or chronic as determined by the PI and/or designee

Locations (1)

Ochsner Clinic Foundation

New Orleans, Louisiana, United States

Outcomes

Primary Outcomes

Radial and Ulnar Arterial Diameter

Radial and ulnar artery diameter was measured at baseline and 60 min after with a Doppler ultrasound system. A marker was used to indicate the site of initial transducer placement on the forearm to ensure that subsequent scans were performed at the same location.

Time frame: 1 hour

Secondary Outcomes

Pain Measured by Numerical Rating Scale

Numerical rating scale pain scores range from 0 (absence of pain) to 10 (worst pain imaginable)

Time frame: 1 month

Data from ClinicalTrials.gov

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