Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of NMB.
The investigators' aim is to prove that half dose sugammadex in combination with neostigmine 0.05 mg/kg is non-inferior to the recommended dose of sugammadex for the reversal of deep ( absence of Trian of Four response :TOF) or moderate ( TOF 1 or 2 twiches) muscle paralysis in patients undergoing surgery under general anesthesia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
56
AUBMC
Beirut, Lebanon
TOF ratio of 0.9
Time frame: within 5 minutes
the time to return of TOF ratio to 0.9 and the time till extubation
Time frame: within 10 minutes
Residual neuro-muscular blockade
Post Anesthesia recovery unit
Time frame: within 10 to 180 mins
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.