Effects of Adding Chickpeas to the American Diet (Long Term Study)

University of Florida12 enrolled

Overview

This prospective study will assess the effects of adding legumes, especially chick peas, to the diet of healthy adults on the commensal bacteria from feces of human subjects and resulting self-reported GI symptoms as well as markers of immune function.

Long-term observational study: Subjects enrolled will participate in an observational setting for three months. During this time period, individuals will be encouraged, to maintain increased legume intake and explore new recipes that allow them to maintain a diverse menu of legume based foods. Fecal samples for microbiota analysis will be collected every month. Participants will record a weekly online questionnaire about legume intake and GI health as well as other health status updates. While participants will be encouraged to maintain regular intake of chickpeas throughout the long-term study, consumption of other legumes will be encouraged.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Inflammation

Interventions

Observational Chickpea DietOTHER

Individuals encouraged to maintain increased legume intake and explore new recipes that allow them to maintain a diverse menu of legume based foods. Fecal samples collected monthly.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Good Health * No systemic antibiotics during the preceding two months * No medication suppressing immune function * Willingness to provide basic demographic as well as medical history data Exclusion Criteria: * Gastric Ulcers * Inflammatory Bowel Disease (IBD) or Irritable Bowel Syndrome (IBS) * Chronic constipation/diarrhea * Body Mass Index (BMI) \> 30 * Dietary restrictions that prevent legume intake * Currently on any medication that can affect GI transit time * Consumption of \>3 servings/week of chickpeas or \>6 servings/week of legumes BEFORE study begins

Locations (1)

Emerging Pathogens Institiute

Gainesville, Florida, United States

Outcomes

Primary Outcomes

Changes in Number of 16S RNA Sequences on Days 31, Day 62, and Day 93.

Compare the gut microbiota composition of individual subjects before and after the implementation of a controlled and observed diet of chickpeas and legume products.

Time frame: Change from Day 31, Day 62, and Day 93

Data from ClinicalTrials.gov

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