DECT Ventilation Imaging

University Hospital, Strasbourg, France10 enrolled

Overview

Demonstrate the feasibility of dual energy computed tomography using Krypton as a gaseous contrast media in order to study the in vivo ventilation. Two different clinical situations will be tested : * Prediction of postoperative pulmonary function for oncologic patients * Detection of Bronchiolitis Obliterans in lung transplant recipients.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

For Oncologic Patients Potentially Operable Lung Tumor With a Recent (Less Than 1 Month) VQ Scan For Lung Transplant Recipients Single of Bilateral Lung Transplant

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion criteria: For oncologic patients : * Potentially operable lung tumor * With a recent (less than 1 month) V/Q scan For lung transplant recipients : * Single of bilateral lung transplant * From 5 months onwards * With recent (less than 1 month) respiratory functional explorations Exclusion criteria: * Impossibility to follow simple orders or control one's respiration * Known Krypton hypersensitivity * History of malignant hyperthermia * Increased intracranial pressure * Minors * Pregnant Women

Outcomes

Primary Outcomes

Image quality on a qualitative 5 levels scale

Time frame: 1 day of DECT ventilation imaging

Secondary Outcomes

Radiation dose

Time frame: 1 day of DECT ventilation imaging

Image noise with measurement of signal to noise and contrast to noise ratios

Time frame: 1 day of DECT ventilation imaging

Total examination time

Time frame: 1 day of DECT ventilation imaging

DECT Ventilation Imaging

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes