The efficiency of non-invasive ventilation (NIV) in hypercapnic patients with chronic obstructive pulmonary disease during pulmonary rehabilitation has been shown in numerous studies. There is only a limited number of therapeutic options for patients with severely progressed interstitial lung disease (ILD). The question whether chronic hypercapnic ILD-patients are able to profit from nocturnal NIV and thus increase their performance in physical training has been left unknown. Therefore, this study aims to evaluate the feasibility of the initialization of a NIV for hypercapnic ILD-patients during pulmonary rehabilitation.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
patients will undergo a nocturnal non-invasive ventilation
Schoen Klinik Berchtesgadener Land
Schönau am Königssee, Bavaria, Germany
RECRUITINGtimespan until sufficient use of noninvasive ventilation > 6h during night
Time frame: day 4-16
6-minute walking test
change in 6-minute walking distance
Time frame: day 1-3 and day 17-19
arterial pressure of carbon dioxide during night
measured transcutaneously by a Sentec device
Time frame: day 1-3 and day 17-19
lung function measured by bodyplethysmograph
measured by bodyplethysmograph
Time frame: day 1-3 and 17-19
energy expenditure during night assessed by Sensewear Armband
assessed by Sensewear Armband
Time frame: day 5 and 15
quality of life
Short-Form-36 health survey, Hospital Anxiety and Depression scale and severe respiratory insufficiency questionnaire
Time frame: day 1-3 and 17-19
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