Effects of Whole-body Vibration Training on Body Composition in Adolescents With and Without Down Syndrome

Universidad de Zaragoza58 enrolled

Overview

The main aims of the present project include 1) to study the longitudinal effects of whole-body vibratory exercise on bone metabolism in adolescents with and without DS and 2) to evaluate whether a low frequency vibratory training program consisting of 3 sessions per week for 9 months (each vibratory session last approximately 10 minutes and includes 5-6 bouts of 1 min with 1 min rest between bouts) can improve bone development in these populations. Finally, and additional aim of the project is 3) to determine how long these effects may last after the end of the intervention.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Down Syndrome

Interventions

Whole-body vibration training (Power Plate®) on bone mass and bone metabolism in adolescents with and without Down syndrome.

Eligibility

Sex: ALLMin age: 10 YearsMax age: 19 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Both groups: Ages 10 - 19. * Both groups: Parental/guardian permission (informed consent) and if appropriate, child verbal assent. * Down syndrome group only: Diagnosis of Down syndrome. Exclusion Criteria: * Taking medication affecting bone. * Non-caucasian.

Outcomes

Primary Outcomes

Changes from baseline in body composition assessed with dual energy X-ray at different time points, 6 months and 15 months.

Time frame: Changes from baseline in body composition at 6 months and changes from baseline in body composition at 15 months

Secondary Outcomes

Changes from baseline in bone structure evaluated with peripheral quantitative computed tomography at different time points, 6 months and 15 months.

Time frame: Changes from baseline in bone structure at 6 months and changes from baseline in bone structure at 15 months