Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment

N/ACompletedNCT02381977

University of Pittsburgh922 enrolled

Overview

PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.

Study Type

OBSERVATIONAL

Enrollment

922

Conditions

Cardiac Arrest Stroke Traumatic Brain Injury Brain Mass Status Epilepticus Spinal Cord Disease Hydrocephalus

Interventions

No interventionOTHER

Eligibility

Sex: ALLMin age: 7 DaysMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Children aged 7 days to 17 years inclusively and admitted to an ICU (ICU can be classified as general, cardiac, trauma, etc). 2. Children with acute or acute on chronic neurologic disease that occurred just prior to hospital admission or occurred during the hospital admission. 3. Acute neurologic disease is secondary to TBI, stroke, brain mass, hydrocephalus, cardiac arrest, status epilepticus, CNS infection/inflammation, or spinal cord injury. Exclusion Criteria: 1. Children with acute perinatal neurologic disease. 2. Children with isolated chronic brain injury and no acute neurologic disease.

Outcomes

Primary Outcomes

Prevalence of acute brain insult

Time frame: 4 days over a 1 year period

Secondary Outcomes

Mortality

Time frame: Hospital discharge or 3 months

Data from ClinicalTrials.gov

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