ARC in Hemorrhagic Stroke

N/ACompletedNCT02386202

University of North Carolina, Chapel Hill80 enrolled

Overview

To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hemorrhagic Stroke Augmented Renal Clearance

Interventions

No interventionOTHER

No interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults ≥ 18 years * Patients with hemorrhagic stroke * Anticipated length of stay in the neuroscience intensive care unit \> 48 hours * Informed consent provided by the patient or by the patient's designated medical proxy Exclusion Criteria: * Pregnancy * Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5) * Patients receiving renal replacement therapy * Patients with an admission serum creatinine \> 1.4 mg/dL * Patients with non-aneurysmal subarachnoid hemorrhage * Patients with history of nephrectomy or body mass index \< 18 kg/m2

Locations (1)

University of North Carolina Hospitals

Chapel Hill, North Carolina, United States

Outcomes

Primary Outcomes

To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke

Daily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge

Time frame: Over neurosciences intensive care unit stay

Data from ClinicalTrials.gov

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