Assessment of the Symbiotic Fermented Milk in Patients With Irritable Bowel Syndrome

Inclusion Criteria: * Confirmed constipation-predominant irritable bowel syndrome (on the basis of Rome III criteria) (≥ 25 % lumpy or hard stools and ≤ 25 % mushy or watery stools). * Meeting Rome III criteria for the determination of irritable bowel syndrome in the last 6 months prior to inclusion and the presence of symptoms such as abdominal pain, bloating and general digestive discomfort at least twice a week in the last 3 months prior to inclusion. * Colonoscopy in the last 7 years prior to inclusion with normal results. Exclusion Criteria: * Diarrhoea-predominant irritable bowel syndrome (≥ 25 % mushy or watery stools and ≤ 25 % lumpy or hard stools). * Clinical signs of alarm, such as rectorrhagia, fever, recent unexplained weight loss. * Organic gastrointestinal diseases, including chronic inflammatory bowel disease and systemic diseases with gastrointestinal difficulties. * Severe abdominal pain and the taking of analgesics or antispasmodics for the previous 5 days or more. * Having begun treatment with psychotropic medicines or other drugs for the treatment of irritable bowel syndrome within the previous month. * Dietary habits that could influence the assessment of the investigational product, such as slimming or a vegetarian diet. * Known allergy to ingredient(s) in the investigational product. * Known medical or psycho-physical condition that is, in the opinion of the investigator, in conflict with consumption of the investigational product and/or the course of the study. * Participation in another clinical study less than one month before inclusion or concurrent participation in another clinical study.