Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

University Hospital, Strasbourg, France76 enrolled

Overview

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Periodontitis Hypertension

Interventions

echo Doppler lower limbsOTHER

Eligibility

Sex: MALEMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * -Men- \>40 years * moderate and severe generalized chronic periodontitis * Former diagnosis of hypertension * \>12 teeth Exclusion Criteria: * \>70 years * smokers (\>10 cig/day) * body mass index\>30 * Need of antibioprophylaxis * Medical treatment including anti-inflammatory drugs and/or antibiotics * Refractory form of hypertension- aggressive periodontitis

Locations (1)

Service de parodontologie

Strasbourg, France

Outcomes

Primary Outcomes

Measuring the thickness of the intima-media

Time frame: 15 days

Secondary Outcomes

Evaluation of anatomical changes that may occur at the arterial level

Time frame: Within 15 days after inclusion

Data from ClinicalTrials.gov

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