Neoadjuvant Chemotherapy Versus Surgery Alone for Esophageal Squamous Cell Carcinoma

Inclusion Criteria: 1. Histologic diagnosis of squamous cell thoracic esophageal carcinoma of Stage IIA to IIIB, (7th Union for International Cancer Control, UICC-TNM). 2. Patients must not have received any prior anticancer therapy of esophageal carcinoma. 3. Age ranges from 18 to 75 years. 4. Without operative contraindication. 5. Absolute white blood cells count ≥4.0×109/L, neutrophil ≥1.5×109/L, platelets ≥100.0×109/L, hemoglobin ≥90g/L, and normal functions of liver and kidney, total bilirubin（TBIL）≤1.5N, aspartate aminotransferase (AST)≤2.5N, alanine aminotransferase(ALT)≤2.5N, prothrombin time(PT)≤1.5N, and activated partial thromboplastin time(APTT) is in normal range, endogenous creatinine clearance rate(CRE)≤1.5N. 6. Patients must not have diagnosed with other cancer and must not received any prior anticancer therapy except prostatic cancer with more than 5 years disease-free survival(DFS). 7. expected R0 resection. 8. ECOG 0～2. 9. Signed informed consent document on file. 10.No metastatic lymph node in cervical by color doppler sonography. Exclusion Criteria: 1. Multiple primary cancer. 2. The subject cannot understand and sign the informed consent form(ICF). 3. Patients with concomitant hemorrhagic disease. 4. Any un expected reason for patients can't get operation. 5. Inability to use gastric conduit after esophagectomy because of a prior surgery. 6. Pregnant or breast feeding. 7. Patients are diagnosed or suspected to be allergic to cisplatin or Paclitaxel.