The Evaluation of Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of JPI-289 in Healthy Male Volunteers

Inclusion Criteria: * 19\~55 years healthy male * BMI measurement 20kg/m²\~27kg/m² * 90 ≤ SBP\<140(mmHg) 60 ≤ DBP\<100(mmHg) 45 ≤ Pulse rate\<100(bpm) * Signed the informed consent form to participate voluntarily and to comply with the trial requirements * For a follow-up visit and during the study period, blood samples and availability Exclusion Criteria: * History of clinically significant hepatic, gastrointestinal, pulmonary, musculoskeletal, endocrine, psychiatric, hematooncologic, cardiovascular (Specially asthma, obstructive pulmonary disease, peptic ulcer) * History of skin disease of graft affecting absorption of the drug * History of drug abuse * Positive urine drug screening * Administrated investigational product in a previous clinical trial within 60 days of the screening test * Donated blood within 60 days prior to screening test